Old Orchard Street, Saco Avenue, Ocean Park Road, Main Street, Elm Street, North Street, Spring Street, Bradley Street, New County Road, Sokokis Trail, Maple Street, Cumberland Street, Depot Road, Pequawket Trail, Portland Street, Lovell Road, Crooked River Causeway, Songo Pond Road, Mayville Road, Ellis River Road, South Main Street
- Direction:
- North/South
- Southern Terminus:
- West Grand Avenue (ME 9) and East Grand Avenue (ME 9) in Old Orchard Beach
- Northern Terminus:
- Elm Street (ME 120) in Andover
- Distance:
- 118.16 miles
- Counties:
- York, Cumberland, Oxford
- Signed:
- Yes
ME 5 is a north/south route through the western portion of Maine. It begins at ME 9 along the waterfront in Old Orchard Beach and runs north to Elm Street (ME 120) in Andover, a few miles north of US 2. There is no direct interchange where it crosses the Maine Turnpike (I-95), but a connection is provided through I-195.
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