North Broadway, South Broadway, Front Street, West Broadway, East Broadway, Main Street, Shiloh Pike, West Broad Street, East Broad Street, East Commerce Street, Bridgeton-Millville Pike, West Main Street, East Main Street
- Direction:
 - East/West
 - Western Terminus:
 - Delaware Memorial Bridge (I-295/US 40) and US 130 in Pennsville
 - Eastern Terminus:
 - NJ 50 in Upper Township
 - Distance:
 - 53.80 miles
 - Counties:
 - Salem, Cumberland, Atlantic, Cape May
 - Signed:
 - Yes
 
NJ 49 is the southernmost major east/west route in New Jersey. US 130 turns into NJ 49 at its southern terminus at the Delaware Memorial Bridge (I-295/US 40). It runs southeast through Salem to Bridgeton and then east through Millville to end at NJ 50 in Upper Township. It is a two-lane undivided road for most of its length, although it briefly widens to four lanes in some areas.
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